Glutamate, Glutamine and GABA Levels in Rat Brain Measured Using MRS, HPLC and NMR Methods in Study of Two Models of Autism

Glutamate, Glutamine and GABA Levels in Rat Brain Measured Using MRS, HPLC and NMR Methods in Study of Two Models of Autism

The disorders of the glutamatergic neurotransmission have been associated with pathogenesis of autism. In this study we evaluated the impact of the in vivo and ex vivo test methodology on measurements of levels of neurotransmitter amino acids in hippocampus of rats for valproic acid- (VPA) and thali...

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Bibliographic Details
Main Authors: Elzbieta Zieminska, Beata Toczylowska, Dominik Diamandakis, Wojciech Hilgier, Robert Kuba Filipkowski, Rafal Polowy, Jaroslaw Orzel, Michal Gorka, Jerzy Wieslaw Lazarewicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
ASD animal models
neurotransmitters
MRS
NMR
HPLC
USV
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00418/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00418/full

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