Cell-Matrix Interactions and Matricrine Signaling in the Pathogenesis of Vascular Calcification

Cell-Matrix Interactions and Matricrine Signaling in the Pathogenesis of Vascular Calcification

Vascular calcification is a complex pathological process occurring in patients with atherosclerosis, type 2 diabetes, and chronic kidney disease. The extracellular matrix, via matricrine-receptor signaling plays important roles in the pathogenesis of calcification. Calcification is mediated by osteo...

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Bibliographic Details
Main Authors: David Ngai, Marsel Lino, Michelle P. Bendeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
vascular calcification
extracellular matrix
mechanotransduction
collagen
integrin
discoidin domain receptor
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00174/full

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https://www.frontiersin.org/article/10.3389/fcvm.2018.00174/full

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