Low-grade nasopharyngeal papillary adenocarcinoma: a case report and review of the literature

• Main Authors: Wang XL, Yan HJ, Luo YJ, Fan TY
• Format: Article
• Language: English
• Published: Dove Medical Press 2016-05-01
• Series: OncoTargets and Therapy
• Subjects: nasopharyngeal adenocarcinoma; immunohistochemistry; treatment policy; survival and prognosis
• Online Access: https://www.dovepress.com/low-grade-nasopharyngeal-papillary-adenocarcinoma-a-case-report-and-re-peer-reviewed-article-OTT

Xiaoli Wang,1,2 Hongjiang Yan,1 Yijun Luo,1,2 Tingyong Fan1 1Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Jinan, 2School of Medicine and Life Sciences, Shandong Academy of Medical Sciences, University of Jinan, Jinan, People’s Republic of China Abstract: Low-grade nasopharyngeal papillary adenocarcinoma is an extremely rare tumor, with only a limited number of cases reported in the literature. Some published studies have paid more attention to the clinicopathological features of nasopharyngeal adenocarcinoma, while little effort has been made to study the optimal therapeutic strategies. We report about a woman diagnosed with low-grade nasopharyngeal papillary adenocarcinoma. She received the treatment approach that combined transnasal endoscopic surgery to remove the lesion with postoperative radiotherapy for nasal cavity. There was no evidence of recurrence after 4 months of surgery, and further follow-up is being continued. Through this example, we wanted to explore the optimal therapeutic strategies for primary nasopharyngeal adenocarcinomas. Keywords: nasopharyngeal adenocarcinoma, immunohistochemistry, treatment policy, survival and prognosis