Influence of the rs1080985 Single Nucleotide Polymorphism of the CYP2D6 Gene and APOE Polymorphism on the Response to Donepezil Treatment in Patients with Alzheimer's Disease in China

Influence of the rs1080985 Single Nucleotide Polymorphism of the CYP2D6 Gene and APOE Polymorphism on the Response to Donepezil Treatment in Patients with Alzheimer's Disease in China

Background/Aim: Recent data have indicated that the rs1080985 single nucleotide polymorphism (SNP) of the cytochrome P450 (CYP) 2D6 and the common apolipoprotein E (APOE) gene may affect the response to donepezil in patients with Alzheimer's disease (AD). We investigated this association in Chi...

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Bibliographic Details
Main Authors: Mengyuan Liu, Ying Zhang, Ya Ruth Huo, Shuling Liu, Shuai Liu, Junwei Wang, Change Wang, Jinhuan Wang, Yong Ji
Format: Article
Language:English
Published: Karger Publishers 2014-11-01
Series:Dementia and Geriatric Cognitive Disorders Extra
Subjects:
Polymorphism
Alzheimer’s disease
Chinese population
Donepezil
CYP2D6
APOE
Online Access:http://www.karger.com/Article/FullText/367596

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