Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway

Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway

The development of chemoresistance to cisplatin regimens causes a poor prognosis in patients with advanced NSCLC. The role of noncanonical Wnt signaling in the regulation of properties of lung cancer stem cells and chemoresistance was interrogated, by accessing capacities of cell proliferation, migr...

Full description

Bibliographic Details
Main Authors:	Jiali Yang, Kangjian Zhang, Jing Wu, Juan Shi, Jing Xue, Jing Li, Juan Chen, Yongzhao Zhu, Jun Wei, Jinxi He, Xiaoming Liu
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2016/1690896

Similar Items

Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca2+ pathways in human osteoarthritis osteoblasts.
by: Xavier Martineau, et al.
Published: (2017-01-01)

Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases
by: Juan Shi, et al.
Published: (2016-01-01)

Wnt5a through noncanonical Wnt/JNK or Wnt/PKC signaling contributes to the differentiation of mesenchymal stem cells into type II alveolar epithelial cells in vitro.
by: Airan Liu, et al.
Published: (2014-01-01)

WNT11-Conditioned Medium Promotes Angiogenesis through the Activation of Non-Canonical WNT-PKC-JNK Signaling Pathway
by: Jingcai Wang, et al.
Published: (2020-10-01)

Distinct Patterns of Wnt3a and Wnt5a Signaling Pathway in the Lung from Rats with Endotoxic Shock.
by: Hiong-Ping Hii, et al.
Published: (2015-01-01)

Investigation of the Wnt5a function in lung cancer and the correlation between Wnt5a and TKI-resistance
by: Jheng-Cheng Huang, et al.
Published: (2015)

WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts
by: Edyta Działo, et al.
Published: (2019-03-01)

CELSR1 Promotes Neuroprotection in Cerebral Ischemic Injury Mainly through the Wnt/PKC Signaling Pathway
by: Li-Hong Wang, et al.
Published: (2020-02-01)

Mechanical Tension Promotes the Osteogenic Differentiation of Rat Tendon-derived Stem Cells Through the Wnt5a/Wnt5b/JNK Signaling Pathway
by: Xiangzhou Liu, et al.
Published: (2015-05-01)

Wnt5a increases cardiac gene expressions of cultured human circulating progenitor cells via a PKC delta activation.
by: Masamichi Koyanagi, et al.
Published: (2009-06-01)

Regulation of lymphangiogenesis by WNT siganlling: Focus on WNT5A
by: Lutze, Grit
Published: (2019)

The Research Progress about Wnt Pathway of Lung Cancer Stem Cells
by: Xiaojiang LI, et al.
Published: (2011-08-01)

The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells
by: Ian J. Huggins, et al.
Published: (2017-10-01)

Wnt5a Signaling in Normal and Cancer Stem Cells
by: Yan Zhou, et al.
Published: (2017-01-01)

WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling
by: Shaojie Jiang, et al.
Published: (2019-08-01)

Wnt5a Increases the Glycolytic Rate and the Activity of the Pentose Phosphate Pathway in Cortical Neurons
by: Pedro Cisternas, et al.
Published: (2016-01-01)

Glioblastoma stem cells and Wnt signaling pathway: molecular mechanisms and therapeutic targets
by: Ruoyu Guan, et al.
Published: (2020-08-01)

PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway
by: Jing Luo, et al.
Published: (2019-04-01)

Wnt/β-Catenin and Wnt5a/Ca2+ Pathways Regulate Proliferation and Apoptosis of Keratinocytes in Psoriasis Lesions
by: Yanfei Zhang, et al.
Published: (2015-07-01)

Wnt5a Affects Schwann Cell Proliferation and Regeneration via Wnt/c-Jun and PTEN Signaling Pathway
by: Fei Yu, et al.
Published: (2018-01-01)

Corrigendum to “Wnt5a Signaling in Normal and Cancer Stem Cells”
by: Yan Zhou, et al.
Published: (2017-01-01)

WNT5B in Physiology and Disease
by: Sarocha Suthon, et al.
Published: (2021-05-01)

Wnt5a Signaling in Cancer
by: Marwa S. Asem, et al.
Published: (2016-08-01)

Paracrine Activation of the Wnt/β-Catenin Pathway by Bone Marrow Stem Cell Attenuates Cisplatin-Induced Kidney Injury
by: Xiaoyan Jiao, et al.
Published: (2017-12-01)

Updating the Wnt pathways
by: Jia Yu, et al.
Published: (2014-10-01)

Methylation of Wnt Antagonist Genes and Wnt5a as Prognostic Markers in Colorectal Cancer
by: Rawson, James B.
Published: (2010)

Methylation of Wnt Antagonist Genes and Wnt5a as Prognostic Markers in Colorectal Cancer
by: Rawson, James B.
Published: (2010)

Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells
by: Yilmaz Mustafa, et al.
Published: (2009-10-01)

Non-canonical Wnt signalling in craniofacial skeletogenesis : role of wls, gpc4, wnt5b and wnt9a
by: Ling, Irving Teck-Cheng
Published: (2018)

Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors
by: Xinhui Wu, et al.
Published: (2019-09-01)

MiR‐191‐5p inhibits lung adenocarcinoma by repressing SATB1 to inhibit Wnt pathway
by: Lai‐yong Zhou, et al.
Published: (2020-01-01)

ING5 inhibits lung cancer invasion and epithelial–mesenchymal transition by inhibiting the WNT/β‐catenin pathway
by: Xin‐Li Liu, et al.
Published: (2019-04-01)

Retinal expression of Wnt-pathway mediated genes in low-density lipoprotein receptor-related protein 5 (Lrp5) knockout mice.
by: Jing Chen, et al.
Published: (2012-01-01)

Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells
by: Lingfeng He, et al.
Published: (2018-08-01)

Wnt blockers inhibit the proliferation of lung cancer stem cells
by: Zhang X, et al.
Published: (2015-04-01)

FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway
by: Shanyang He, et al.
Published: (2021-01-01)

Corrigendum: WNT5B in Physiology and Disease
by: Sarocha Suthon, et al.
Published: (2021-07-01)

Wnt5a Signaling in Gastric Cancer
by: Pablo Astudillo
Published: (2020-03-01)

Wnt5 signaling in vertebrate pancreas development
by: Petryk Anna, et al.
Published: (2005-10-01)

miR-140-5p regulates the odontoblastic differentiation of dental pulp stem cells via the Wnt1/β-catenin signaling pathway
by: Xiaohui Lu, et al.
Published: (2019-07-01)

Cannot write session to /tmp/vufind_sessions/sess_3712ch2mkk5n00ck34l4jof71r