Determination of the vildagliptin intermediate enantiomer by chiralce-columns

In order to establish a NP-HPLC method for the determination of enantiomer in vildagliptin intermediate, the determination is carried out on the column of ChiralpakAD-H(250 mm×4.6 mm, 5 μm), with the mobile phase of n-hexane, ethanol and methanol(volume ratio of 65∶25∶10)at flow rate of 0.8 mL/min....

Full description

Bibliographic Details
Main Authors: Weina LI, Jia HU, Mengyu ZHAI, Zibin GAO
Format: Article
Language:zho
Published: Hebei University of Science and Technology 2017-06-01
Series:Journal of Hebei University of Science and Technology
Subjects:
Online Access:http://xuebao.hebust.edu.cn/hbkjdx/ch/reader/create_pdf.aspx?file_no=b201703006&flag=1&journal_