Determination of the vildagliptin intermediate enantiomer by chiralce-columns
In order to establish a NP-HPLC method for the determination of enantiomer in vildagliptin intermediate, the determination is carried out on the column of ChiralpakAD-H(250 mm×4.6 mm, 5 μm), with the mobile phase of n-hexane, ethanol and methanol(volume ratio of 65∶25∶10)at flow rate of 0.8 mL/min....
Main Authors: | , , , |
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Format: | Article |
Language: | zho |
Published: |
Hebei University of Science and Technology
2017-06-01
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Series: | Journal of Hebei University of Science and Technology |
Subjects: | |
Online Access: | http://xuebao.hebust.edu.cn/hbkjdx/ch/reader/create_pdf.aspx?file_no=b201703006&flag=1&journal_ |