Hyperpolarized Amino Acid Derivatives as Multivalent Magnetic Resonance pH Sensor Molecules

Hyperpolarized Amino Acid Derivatives as Multivalent Magnetic Resonance pH Sensor Molecules

pH is a tightly regulated physiological parameter that is often altered in diseased states like cancer. The development of biosensors that can be used to non-invasively image pH with hyperpolarized (HP) magnetic resonance spectroscopic imaging has therefore recently gained tremendous interest. Howev...

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Bibliographic Details
Main Authors:	Christian Hundshammer, Stephan Düwel, David Ruseckas, Geoffrey Topping, Piotr Dzien, Christoph Müller, Benedikt Feuerecker, Jan B. Hövener, Axel Haase, Markus Schwaiger, Steffen J. Glaser, Franz Schilling
Format:	Article
Language:	English
Published:	MDPI AG 2018-02-01
Series:	Sensors
Subjects:	pH sensors hyperpolarized dissolution dynamic nuclear polarization magnetic resonance spectroscopic imaging nuclear magnetic resonance amino acids
Online Access:	http://www.mdpi.com/1424-8220/18/2/600

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