Crystal Structure of NADPH-Dependent Methylglyoxal Reductase Gre2 from <i>Candida Albicans</i>

Crystal Structure of NADPH-Dependent Methylglyoxal Reductase Gre2 from <i>Candida Albicans</i>

Gre2 is a key enzyme in the methylglyoxal detoxification pathway; it uses NADPH or NADH as an electron donor to reduce the cytotoxic methylglyoxal to lactaldehyde. This enzyme is a member of the short-chain dehydrogenase/reductase (SDR) superfamily whose members catalyze this type of reaction with a...

Full description

Bibliographic Details
Main Authors: Giang Thu Nguyen, Shinae Kim, Hyeonseok Jin, Dong-Hyung Cho, Hang-Suk Chun, Woo-Keun Kim, Jeong Ho Chang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Crystals
Subjects:
Gre2
methylglyoxal reductase
NADPH
SDR family
<i>Candida albicans</i>
Online Access:https://www.mdpi.com/2073-4352/9/9/471

Similar Items

Similar Items