The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension
Objective: The pathogenesis for hypertension is complicated. Except environmental factors, genetic variations are a large part of reasons account for hypertension. With the rapid development of sequencing techniques, genome wide association study (GWAS) provide an effective method for understandi...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Editorial Board of Journal of Hainan Medical University
2019-10-01
|
Series: | Journal of Hainan Medical University |
Subjects: | |
Online Access: | http://www.hnykdxxb.com/PDF/201910/15.pdf |
id |
doaj-9db1993b36f946cc8b02c138b4d96bee |
---|---|
record_format |
Article |
spelling |
doaj-9db1993b36f946cc8b02c138b4d96bee2020-11-25T01:01:47ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372019-10-0125206773The Genetic Polymorphism of ATP2B1 associated with Essential HypertensionFan-Li Huang0Hao Sun1Institute of Medical Biology Chinese Academy of Medical SciencesInstitute of Medical Biology Chinese Academy of Medical SciencesObjective: The pathogenesis for hypertension is complicated. Except environmental factors, genetic variations are a large part of reasons account for hypertension. With the rapid development of sequencing techniques, genome wide association study (GWAS) provide an effective method for understanding the complicated genetic backgroundof multifactorial diseases. More than 150 genes associated with essential hypertension were knew today, of which, ATP2B1 is most prominent. Whether in Europe or in East Asia, the association between essential hypertension and ATP2B1 is statistically significant in different people with different genetic background. Here we reviewed the relationship between genetic polymorphisms of ATP2B1 and essential hypertension.http://www.hnykdxxb.com/PDF/201910/15.pdf atp2b1hypertensiongenetic |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Fan-Li Huang Hao Sun |
spellingShingle |
Fan-Li Huang Hao Sun The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension Journal of Hainan Medical University atp2b1 hypertension genetic |
author_facet |
Fan-Li Huang Hao Sun |
author_sort |
Fan-Li Huang |
title |
The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension |
title_short |
The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension |
title_full |
The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension |
title_fullStr |
The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension |
title_full_unstemmed |
The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension |
title_sort |
genetic polymorphism of atp2b1 associated with essential hypertension |
publisher |
Editorial Board of Journal of Hainan Medical University |
series |
Journal of Hainan Medical University |
issn |
1007-1237 1007-1237 |
publishDate |
2019-10-01 |
description |
Objective: The pathogenesis for hypertension is complicated. Except environmental factors,
genetic variations are a large part of reasons account for hypertension. With the rapid
development of sequencing techniques, genome wide association study (GWAS) provide
an effective method for understanding the complicated genetic backgroundof multifactorial
diseases. More than 150 genes associated with essential hypertension were knew today, of
which, ATP2B1 is most prominent. Whether in Europe or in East Asia, the association between
essential hypertension and ATP2B1 is statistically significant in different people with different
genetic background. Here we reviewed the relationship between genetic polymorphisms of
ATP2B1 and essential hypertension. |
topic |
atp2b1 hypertension genetic |
url |
http://www.hnykdxxb.com/PDF/201910/15.pdf |
work_keys_str_mv |
AT fanlihuang thegeneticpolymorphismofatp2b1associatedwithessentialhypertension AT haosun thegeneticpolymorphismofatp2b1associatedwithessentialhypertension AT fanlihuang geneticpolymorphismofatp2b1associatedwithessentialhypertension AT haosun geneticpolymorphismofatp2b1associatedwithessentialhypertension |
_version_ |
1725207417404260352 |