The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension

Objective: The pathogenesis for hypertension is complicated. Except environmental factors, genetic variations are a large part of reasons account for hypertension. With the rapid development of sequencing techniques, genome wide association study (GWAS) provide an effective method for understandi...

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Main Authors: Fan-Li Huang, Hao Sun
Format: Article
Language:English
Published: Editorial Board of Journal of Hainan Medical University 2019-10-01
Series:Journal of Hainan Medical University
Subjects:
Online Access:http://www.hnykdxxb.com/PDF/201910/15.pdf
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spelling doaj-9db1993b36f946cc8b02c138b4d96bee2020-11-25T01:01:47ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372019-10-0125206773The Genetic Polymorphism of ATP2B1 associated with Essential HypertensionFan-Li Huang0Hao Sun1Institute of Medical Biology Chinese Academy of Medical SciencesInstitute of Medical Biology Chinese Academy of Medical SciencesObjective: The pathogenesis for hypertension is complicated. Except environmental factors, genetic variations are a large part of reasons account for hypertension. With the rapid development of sequencing techniques, genome wide association study (GWAS) provide an effective method for understanding the complicated genetic backgroundof multifactorial diseases. More than 150 genes associated with essential hypertension were knew today, of which, ATP2B1 is most prominent. Whether in Europe or in East Asia, the association between essential hypertension and ATP2B1 is statistically significant in different people with different genetic background. Here we reviewed the relationship between genetic polymorphisms of ATP2B1 and essential hypertension.http://www.hnykdxxb.com/PDF/201910/15.pdf atp2b1hypertensiongenetic
collection DOAJ
language English
format Article
sources DOAJ
author Fan-Li Huang
Hao Sun
spellingShingle Fan-Li Huang
Hao Sun
The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension
Journal of Hainan Medical University
atp2b1
hypertension
genetic
author_facet Fan-Li Huang
Hao Sun
author_sort Fan-Li Huang
title The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension
title_short The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension
title_full The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension
title_fullStr The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension
title_full_unstemmed The Genetic Polymorphism of ATP2B1 associated with Essential Hypertension
title_sort genetic polymorphism of atp2b1 associated with essential hypertension
publisher Editorial Board of Journal of Hainan Medical University
series Journal of Hainan Medical University
issn 1007-1237
1007-1237
publishDate 2019-10-01
description Objective: The pathogenesis for hypertension is complicated. Except environmental factors, genetic variations are a large part of reasons account for hypertension. With the rapid development of sequencing techniques, genome wide association study (GWAS) provide an effective method for understanding the complicated genetic backgroundof multifactorial diseases. More than 150 genes associated with essential hypertension were knew today, of which, ATP2B1 is most prominent. Whether in Europe or in East Asia, the association between essential hypertension and ATP2B1 is statistically significant in different people with different genetic background. Here we reviewed the relationship between genetic polymorphisms of ATP2B1 and essential hypertension.
topic atp2b1
hypertension
genetic
url http://www.hnykdxxb.com/PDF/201910/15.pdf
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