The uptake of soluble and particulate antigens by epithelial cells in the mouse small intestine.
Intestinal epithelial cells (IECs) overlying the villi play a prominent role in absorption of digested nutrients and establish a barrier that separates the internal milieu from potentially harmful microbial antigens. Several mechanisms by which antigens of dietary and microbial origin enter the body...
Main Authors: | Savannah E Howe, Duane J Lickteig, Kyle N Plunkett, Jan S Ryerse, Vjollca Konjufca |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3903549?pdf=render |
Similar Items
-
Systemic and Mucosal Antibody Responses to Soluble and Nanoparticle-Conjugated Antigens Administered Intranasally
by: Savannah E. Howe, et al.
Published: (2016-10-01) -
INTERNALIZATION AND IMMUNOGENICITY OF MUCOSALLY-ADMINISTERED SOLUBLE AND PARTICULATE ANTIGENS
by: Howe, Savannah Ellyse
Published: (2017) -
Protein-coated nanoparticles are internalized by the epithelial cells of the female reproductive tract and induce systemic and mucosal immune responses.
by: Savannah E Howe, et al.
Published: (2014-01-01) -
Per-oral immunization with antigen-conjugated nanoparticles followed by sub-cutaneous boosting immunization induces long-lasting mucosal and systemic antibody responses in mice.
by: Savannah E Howe, et al.
Published: (2015-01-01) -
Dissemination of Chlamydia from the reproductive tract to the gastro-intestinal tract occurs in stages and relies on Chlamydia transport by host cells.
by: Savannah E Howe, et al.
Published: (2019-12-01)