Growth differentiation factor 15 promotes blood vessel growth by stimulating cell cycle progression in repair of critical-sized calvarial defect
Abstract Repair of large bone defects remains a challenge for surgeons, tissue engineering represents a promising approach. However, the use of this technique is limited by delayed vascularization in central regions of the scaffold. Growth differentiation factor 15(GDF15) has recently been reported...
Main Authors: | Shaoyi Wang, Mengyu Li, Wenjie Zhang, Hongfei Hua, Ningtao Wang, Jun Zhao, Jing Ge, Xinquan Jiang, Zhiyuan Zhang, Dongxia Ye, Chi Yang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-09210-4 |
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