Population pharmacokinetic model of cefazolin in total hip arthroplasty
Abstract Cefazolin is an antibiotic recommended for infection prevention in total hip arthroplasty (THA). However, the dosing regimen necessary to achieve therapeutic concentrations in obese patients remains unclear. The aim of this study was to conduct a population analysis of cefazolin pharmacokin...
Main Authors: | J. Lanoiselée, R. Chaux, S. Hodin, S. Bourayou, A. Gibert, R. Philippot, S. Molliex, P. J. Zufferey, X. Delavenne, E. Ollier |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-10-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-99162-7 |
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