Polymorphisms in the TGFB1 and IL2RA genes are associated with clinical forms of leprosy in Brazilian population

Polymorphisms in the TGFB1 and IL2RA genes are associated with clinical forms of leprosy in Brazilian population

BACKGROUND Leprosy is a chronic infectious disease caused by Mycobacterium leprae, and compromises the skin and peripheral nerves. This disease has been classified as multibacillary (MB) or paucibacillary (PB) depending on the host immune response. Genetic epidemiology studies in leprosy have shown...

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Bibliographic Details
Main Authors: Rodrigo Mendes de Camargo, Weber Laurentino da Silva, Priscila Medeiros, Andrea de Faria Fernandes Belone, Ana Carla Pereira Latini
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2018-12-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
leprosy
genetic epidemiology
TGFB1
IL2RA
Tregs
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018001200304&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018001200304&lng=en&tlng=en

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