Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach

Detecting metastatic cells in tumor/lymph node samples of breast cancer patients is extremely important for diagnosis. Here the authors develop a microelectronic biochip that detect the presence of invasive/metastatic cells in unprocessed biopsies and performs better than the current gold standards.

Bibliographic Details
Main Authors: Mohammad Saeid Nikshoar, Mohammad Ali Khayamian, Saeid Ansaryan, Hassan Sanati, Milad Gharooni, Leila Farahmand, Farshad Rezakhanloo, Keivan Majidzadeh-A, Parisa Hoseinpour, Shahrzad Dadgari, Leila Kiani-M, Mohammad Saqafi, Masoumeh Gity, Mohammad Abdolahad
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02184-x
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spelling doaj-9d694c263e764f0b9b2736906ad8c1bd2021-05-11T07:45:00ZengNature Publishing GroupNature Communications2041-17232017-12-018111410.1038/s41467-017-02184-xMetas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approachMohammad Saeid Nikshoar0Mohammad Ali Khayamian1Saeid Ansaryan2Hassan Sanati3Milad Gharooni4Leila Farahmand5Farshad Rezakhanloo6Keivan Majidzadeh-A7Parisa Hoseinpour8Shahrzad Dadgari9Leila Kiani-M10Mohammad Saqafi11Masoumeh Gity12Mohammad Abdolahad13Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranIntegrative Oncology Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECRNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranGenetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECRNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranGenetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECRCentral lab of Pathobiology, Department of Pathology, Breast Cancer Research Center, Motamed Cancer Institute, ACECRDepartment of Radiology, Breast Cancer Research Center, Motamed Cancer Institute, ACECRDepartment of Radiology, Breast Cancer Research Center, Motamed Cancer Institute, ACECRNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranAdvanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical SciencesNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranDetecting metastatic cells in tumor/lymph node samples of breast cancer patients is extremely important for diagnosis. Here the authors develop a microelectronic biochip that detect the presence of invasive/metastatic cells in unprocessed biopsies and performs better than the current gold standards.https://doi.org/10.1038/s41467-017-02184-x
collection DOAJ
language English
format Article
sources DOAJ
author Mohammad Saeid Nikshoar
Mohammad Ali Khayamian
Saeid Ansaryan
Hassan Sanati
Milad Gharooni
Leila Farahmand
Farshad Rezakhanloo
Keivan Majidzadeh-A
Parisa Hoseinpour
Shahrzad Dadgari
Leila Kiani-M
Mohammad Saqafi
Masoumeh Gity
Mohammad Abdolahad
spellingShingle Mohammad Saeid Nikshoar
Mohammad Ali Khayamian
Saeid Ansaryan
Hassan Sanati
Milad Gharooni
Leila Farahmand
Farshad Rezakhanloo
Keivan Majidzadeh-A
Parisa Hoseinpour
Shahrzad Dadgari
Leila Kiani-M
Mohammad Saqafi
Masoumeh Gity
Mohammad Abdolahad
Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
Nature Communications
author_facet Mohammad Saeid Nikshoar
Mohammad Ali Khayamian
Saeid Ansaryan
Hassan Sanati
Milad Gharooni
Leila Farahmand
Farshad Rezakhanloo
Keivan Majidzadeh-A
Parisa Hoseinpour
Shahrzad Dadgari
Leila Kiani-M
Mohammad Saqafi
Masoumeh Gity
Mohammad Abdolahad
author_sort Mohammad Saeid Nikshoar
title Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
title_short Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
title_full Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
title_fullStr Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
title_full_unstemmed Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
title_sort metas-chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-12-01
description Detecting metastatic cells in tumor/lymph node samples of breast cancer patients is extremely important for diagnosis. Here the authors develop a microelectronic biochip that detect the presence of invasive/metastatic cells in unprocessed biopsies and performs better than the current gold standards.
url https://doi.org/10.1038/s41467-017-02184-x
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