Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
Detecting metastatic cells in tumor/lymph node samples of breast cancer patients is extremely important for diagnosis. Here the authors develop a microelectronic biochip that detect the presence of invasive/metastatic cells in unprocessed biopsies and performs better than the current gold standards.
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-12-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-02184-x |
id |
doaj-9d694c263e764f0b9b2736906ad8c1bd |
---|---|
record_format |
Article |
spelling |
doaj-9d694c263e764f0b9b2736906ad8c1bd2021-05-11T07:45:00ZengNature Publishing GroupNature Communications2041-17232017-12-018111410.1038/s41467-017-02184-xMetas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approachMohammad Saeid Nikshoar0Mohammad Ali Khayamian1Saeid Ansaryan2Hassan Sanati3Milad Gharooni4Leila Farahmand5Farshad Rezakhanloo6Keivan Majidzadeh-A7Parisa Hoseinpour8Shahrzad Dadgari9Leila Kiani-M10Mohammad Saqafi11Masoumeh Gity12Mohammad Abdolahad13Nano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranIntegrative Oncology Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECRNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranGenetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECRNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranGenetics Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECRCentral lab of Pathobiology, Department of Pathology, Breast Cancer Research Center, Motamed Cancer Institute, ACECRDepartment of Radiology, Breast Cancer Research Center, Motamed Cancer Institute, ACECRDepartment of Radiology, Breast Cancer Research Center, Motamed Cancer Institute, ACECRNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranAdvanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical SciencesNano Bio Electronic Devices Lab, School of Electrical and Computer Engineering, College of Engineering, University of TehranDetecting metastatic cells in tumor/lymph node samples of breast cancer patients is extremely important for diagnosis. Here the authors develop a microelectronic biochip that detect the presence of invasive/metastatic cells in unprocessed biopsies and performs better than the current gold standards.https://doi.org/10.1038/s41467-017-02184-x |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mohammad Saeid Nikshoar Mohammad Ali Khayamian Saeid Ansaryan Hassan Sanati Milad Gharooni Leila Farahmand Farshad Rezakhanloo Keivan Majidzadeh-A Parisa Hoseinpour Shahrzad Dadgari Leila Kiani-M Mohammad Saqafi Masoumeh Gity Mohammad Abdolahad |
spellingShingle |
Mohammad Saeid Nikshoar Mohammad Ali Khayamian Saeid Ansaryan Hassan Sanati Milad Gharooni Leila Farahmand Farshad Rezakhanloo Keivan Majidzadeh-A Parisa Hoseinpour Shahrzad Dadgari Leila Kiani-M Mohammad Saqafi Masoumeh Gity Mohammad Abdolahad Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach Nature Communications |
author_facet |
Mohammad Saeid Nikshoar Mohammad Ali Khayamian Saeid Ansaryan Hassan Sanati Milad Gharooni Leila Farahmand Farshad Rezakhanloo Keivan Majidzadeh-A Parisa Hoseinpour Shahrzad Dadgari Leila Kiani-M Mohammad Saqafi Masoumeh Gity Mohammad Abdolahad |
author_sort |
Mohammad Saeid Nikshoar |
title |
Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach |
title_short |
Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach |
title_full |
Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach |
title_fullStr |
Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach |
title_full_unstemmed |
Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach |
title_sort |
metas-chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2017-12-01 |
description |
Detecting metastatic cells in tumor/lymph node samples of breast cancer patients is extremely important for diagnosis. Here the authors develop a microelectronic biochip that detect the presence of invasive/metastatic cells in unprocessed biopsies and performs better than the current gold standards. |
url |
https://doi.org/10.1038/s41467-017-02184-x |
work_keys_str_mv |
AT mohammadsaeidnikshoar metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT mohammadalikhayamian metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT saeidansaryan metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT hassansanati metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT miladgharooni metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT leilafarahmand metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT farshadrezakhanloo metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT keivanmajidzadeha metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT parisahoseinpour metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT shahrzaddadgari metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT leilakianim metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT mohammadsaqafi metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT masoumehgity metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach AT mohammadabdolahad metaschippreciselyidentifiespresenceofmicrometastasisinlivebiopsysamplesbylabelfreeapproach |
_version_ |
1721451664236347392 |