White blood cell count and clustered components of metabolic syndrome: A study in western Iran

• Main Authors: Mohammad Taghi Hedayati, Mahdi Montazeri, Negin Rashidi, Elham Yousefi abdolmaleki, Mohammad-Ali Shafiee, Ali Maleki, Maryam Farmani, Mohammad Montazeri
• Format: Article
• Language: English
• Published: Babol University of Medical Sciences 2021-01-01
• Series: Caspian Journal of Internal Medicine
• Subjects: metabolic syndrome; white blood cell; inflammation
• Online Access: http://caspjim.com/article-1-1842-en.html
• ISSN: 2008-6164; 2008-6172

Background: White blood cell count (WBC) is one of the objective parameters of systemic inflammation. The aim of present study was to evaluate the relationship between WBC count and metabolic syndrome. Methods: In this study on Lor population in Borujerd province (West of Iran), from 2011 to 2013, 800 persons were enrolled. MetS was defined based on ATP III criteria. Differences among the quartiles of WBC were examined by one-way analysis of variance. Results: Only 14.7% did not have any of the five components and 43% of all subjects had metabolic syndrome. The means of WBC count in MetS group were significantly higher than the control group (p<0.0001). In subjects without any MetS components, the means of WBC was 5.321 /µL, and it was 5.664, 5.714, 5.961, 6.302, and 6.572 /µL in subjects with 1, 2, 3, 4, and 5 components, respectively. These differences show a significant increasing trend (p<0.0001). Conclusion: WBC count was associated with clustered components of metabolic syndrome. It seems that WBC counts could be considered as a predictive factor for metabolic syndrome in preventive medicine.a