Long-term exposure to pemetrexed induces chronic renal dysfunction in patients with advanced and recurrent non-squamous cell lung cancer: a retrospective study

Abstract Background Pemetrexed (PEM) is administered over a long term to patients with non-squamous cell lung cancer as a maintenance therapy after platinum combination induction chemotherapy. Although decreased renal function owing to long-term PEM exposure has been reported, changes in the renal f...

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Bibliographic Details
Main Authors: Kengo Umehara, Kaori Yama, Nozomi Koike, Shintarou Takayama, Azusa Wakamoto, Tae Hatuyama, Michiya Kobayashi, Hideki Sato
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Renal Replacement Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41100-020-00292-x