TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling

TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling

Abstract Osteoporosis is an osteolytic disorder commonly associated with excessive osteoclast formation. Transcriptional coactivator with PDZ-binding motif (TAZ) is a key downstream effector of the Hippo signaling pathway; it was suggested to be involved in the regulation of bone homeostasis. Howeve...

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Bibliographic Details
Main Authors:	Wanlei Yang, Xuanyuan Lu, Tan Zhang, Weiqi Han, Jianlei Li, Wei He, Yewei Jia, Kangxian Zhao, An Qin, Yu Qian
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-07-01
Series:	Bone Research
Online Access:	https://doi.org/10.1038/s41413-021-00151-3

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