TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling
Abstract Osteoporosis is an osteolytic disorder commonly associated with excessive osteoclast formation. Transcriptional coactivator with PDZ-binding motif (TAZ) is a key downstream effector of the Hippo signaling pathway; it was suggested to be involved in the regulation of bone homeostasis. Howeve...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-07-01
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| Series: | Bone Research |
| Online Access: | https://doi.org/10.1038/s41413-021-00151-3 |