Phenolic Alkaloids from Menispermum dauricum Rhizome Protect against Brain Ischemia Injury via Regulation of GLT-1, EAAC1 and ROS Generation

Phenolic Alkaloids from Menispermum dauricum Rhizome Protect against Brain Ischemia Injury via Regulation of GLT-1, EAAC1 and ROS Generation

Menispermum dauricum rhizome has been widely used in China to treat various cardiovascular and thrombosis disorders. Some studies have reported that the phenolic alkaloids of Menispermum dauricum rhizome (PAM) have protective effects against brain ischemia injury, but the mechanism of this action re...

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Bibliographic Details
Main Authors: Lian-Jun Guo, Jie Ding, Jin-Jin Zhan, Mei Zhou, Xi Sun, Yang Chen, Bo Zhao
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Molecules
Subjects:
Menispermum dauricum
phenolic alkaloids
brain ischemia-reperfusion
glutamate transporter
reactive oxygen species
Online Access:http://www.mdpi.com/1420-3049/17/3/2725/

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