sPLA2-IIA Augments Oxidized LDL-Induced MCP-1 Expression in Vitro Through Activation of Akt

sPLA2-IIA Augments Oxidized LDL-Induced MCP-1 Expression in Vitro Through Activation of Akt

Background/Aims: Group IIA secretory phospholipase A2 (sPLA2-IIA) has an important role in atherosclerosis. In this study, we explored whether sPLA2-IIA overexpression could promote atherosclerosis in normal environment alone or with other inflammatory factors. Methods: Human aortic smooth muscle ce...

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Bibliographic Details
Main Authors: Yongjun Guo, Bo Li, Xuejing Xu, Rong Wu, Weihua Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
MCP-1
Akt
Lv-GFP-sPLA2-IIA
Atherosclerosis
Oxidized LDL
Online Access:http://www.karger.com/Article/FullText/430255

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