Effect of acute fentanyl treatment on synaptic plasticity in the hippocampal CA1 region in rats

Effect of acute fentanyl treatment on synaptic plasticity in the hippocampal CA1 region in rats

Postoperative cognitive dysfunction (POCD), mainly characterized by short-term decline of learning and memory, occurs after operations under anesthesia. However, the underlying mechanisms are poorly understood. The μ-opioid receptors (MOR) are highly expressed in interneurons of hippocampus, and is...

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Bibliographic Details
Main Authors: Hai eTian, Yueming eXu, Fucun eLiu, Guowei eWang, Sanjue eHu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Pharmacology
Subjects:
Fentanyl
Hippocampus
Interneurons
LTP
μ-opioid receptor
FEPSP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00251/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00251/full

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