Advancements in Nucleic Acid Based Therapeutics against Respiratory Viral Infections

Advancements in Nucleic Acid Based Therapeutics against Respiratory Viral Infections

Several viruses cause pulmonary infections due to their shared tropism with cells of the respiratory tract. These respiratory problems due to viral infection become a public health concern due to rapid transmission through air/aerosols or via direct-indirect contact with infected persons. In additio...

Full description

Bibliographic Details
Main Authors:	Kumari Asha, Prashant Kumar, Melvin Sanicas, Clement A. Meseko, Madhu Khanna, Binod Kumar
Format:	Article
Language:	English
Published:	MDPI AG 2018-12-01
Series:	Journal of Clinical Medicine
Subjects:	nucleic acid therapy siRNA ribozyme aptamers DNAzyme influenza virus RSV SARS-CoV adenovirus antiviral drugs
Online Access:	https://www.mdpi.com/2077-0383/8/1/6

Similar Items

Locked and Unlocked Nucleosides in Functional Nucleic Acids
by: Birte Vester, et al.
Published: (2011-05-01)

Recent Advances in Oligonucleotide Therapeutics in Oncology
by: Haoyu Xiong, et al.
Published: (2021-03-01)

The Application of Ribozymes and DNAzymes in Muscle and Brain
by: Leonidas A. Phylactou, et al.
Published: (2010-08-01)

Modified Nucleoside Triphosphates for in-vitro Selection Techniques
by: Adolfo Marcelo Iribarren, et al.
Published: (2016-05-01)

Functional Nucleic Acid-Based Live-Cell Fluorescence Imaging
by: Yutong Zhang, et al.
Published: (2020-12-01)

Thermal Stability of siRNA Modulates Aptamer- conjugated siRNA Inhibition
by: Alexey Berezhnoy, et al.
Published: (2012-01-01)

In Vitro and Ex Vivo Selection Procedures for Identifying Potentially Therapeutic DNA and RNA Molecules
by: Soledad Marton, et al.
Published: (2010-06-01)

RNA Interference as a Prospective Tool for the Control of Human Viral Infections
by: Alesia Levanova, et al.
Published: (2018-09-01)

Modified Nucleic Acids: Expanding the Capabilities of Functional Oligonucleotides
by: Steven Ochoa, et al.
Published: (2020-10-01)

At the Intersection of Biomaterials and Gene Therapy: Progress in Non-viral Delivery of Nucleic Acids
by: Hasan Uludag, et al.
Published: (2019-06-01)

Studies toward biomimetic claisen condensation using nucleic acid templates and ribozyme catalysis
by: Ryu, Youngha
Published: (2005)

Peptide Antiviral Strategies as an Alternative to Treat Lower Respiratory Viral Infections
by: Origène Nyanguile
Published: (2019-06-01)

Self-Assembly of Functional Nucleic Acid-Based Colorimetric Competition Assay for the Detection of Immunoglobulin E
by: Xuexia Lin, et al.
Published: (2019-05-01)

Model-driven engineering of nucleic acid catalysts
by: Chen, Xi, 1983-
Published: (2012)

Covalent and Noncovalent Functionalization of Graphene Oxide with DNA for Smart Sensing
by: Anand Lopez, et al.
Published: (2020-11-01)

In vitro Selection of Chemically Modified DNAzymes
by: Prof. Po‐Jung Jimmy Huang, et al.
Published: (2020-10-01)

5′ Unlocked Nucleic Acid Modification Improves siRNA Targeting
by: Nicholas M Snead, et al.
Published: (2013-01-01)

One Step Histological Detection and Staining of the PTEN Tumor Suppressor Protein by a Single Strand DNA
by: Gloria Longinotti, et al.
Published: (2021-01-01)

Catalytic Activities of Ribozymes and DNAzymes in Water and Mixed Aqueous Media
by: Shu-ichi Nakano, et al.
Published: (2017-11-01)

Formulation‐based approaches for dermal delivery of vaccines and therapeutic nucleic acids: Recent advances and future perspectives
by: Marwa A. Sallam, et al.
Published: (2021-09-01)

Short-interfering RNAs as antivirals against rabies
by: Paulo Eduardo Brandão, et al.

Development and Clinical Trials of Nucleic Acid Medicines for Pancreatic Cancer Treatment
by: Keiko Yamakawa, et al.
Published: (2019-08-01)

GENDEN TEDAVİYE YENİ YAKLAŞIMLAR: KODLAMAYAN NÜKLEİK ASİTLER
by: Hasret Ecevit, et al.
Published: (2015-03-01)

Nucleoside Triphosphates &#8212; Building Blocks for the Modification of Nucleic Acids
by: Marcel Hollenstein
Published: (2012-11-01)

Research progress of siRNA in anti-influenza viral infection
by: Han Li
Published: (2018-06-01)

Hairpin Ribozyme Genes Curtail Alcohol Drinking: from Rational Design to in vivo Effects in the Rat
by: Amalia Sapag, et al.
Published: (2016-01-01)

CD4 Aptamer-SiRNA Chimeras (CD4-AsiCs) Knockdown Gene Expression in CD4+ Cells and Inhibit HIV Transmission
by: Wheeler, Lee Adam
Published: (2013)

Functional analysis of tumor metastasis: modeling colon cancer
by: Philip Y. Wai, et al.
Published: (2011-12-01)

Functional analysis of tumor metastasis: modeling colon cancer
by: Philip Y. Wai, et al.
Published: (2011-12-01)

Molecular Modeling Applied to Nucleic Acid-Based Molecule Development
by: Arne Krüger, et al.
Published: (2018-08-01)

Key Aspects of Nucleic Acid Library Design for in Vitro Selection
by: Maria A. Vorobyeva, et al.
Published: (2018-02-01)

Riboswitches for Controlled Expression of Therapeutic Transgenes Delivered by Adeno-Associated Viral Vectors
by: Zachary J. Tickner, et al.
Published: (2021-06-01)

Inibição da replicação do virus da raiva in vitro e in vivo por meio de interferência por RNA
by: Ekaterina Alexandrovna Durymanova Ono
Published: (2010)

Inibição da replicação do virus da raiva in vitro e in vivo por meio de interferência por RNA
by: Ono, Ekaterina Alexandrovna Durymanova
Published: (2010)

Aptamers
Published: (2018)

Nucleic Acids for Ultra-Sensitive Protein Detection
by: Dragana Spasic, et al.
Published: (2013-01-01)

Nucleic Acid Aptamer: A Novel Potential Diagnostic and Therapeutic Tool for Leukemia
by: Tan Y, et al.
Published: (2019-12-01)

DNA Catalysis: The Chemical Repertoire of DNAzymes
by: Marcel Hollenstein
Published: (2015-11-01)

STAT3 Gene Silencing by Aptamer-siRNA Chimera as Selective Therapeutic for Glioblastoma
by: Carla Lucia Esposito, et al.
Published: (2018-03-01)

The use of oligonucleotide aptamers in cancer therapy
by: Adrian Odrzywolski, et al.
Published: (2016-05-01)