Identification of Pyruvate Dehydrogenase E1 as a Potential Target against <i>Magnaporthe oryzae</i> through Experimental and Theoretical Investigation

Identification of Pyruvate Dehydrogenase E1 as a Potential Target against <i>Magnaporthe oryzae</i> through Experimental and Theoretical Investigation

<i>Magnaporthe oryzae</i> (<i>M. oryzae</i>) is a typical cause of rice blast in agricultural production. Isobavachalcone (IBC), an active ingredient of <i>Psoralea corylifolia</i> L. extract, is an effective fungicide against rice blast. To determine the mechanis...

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Bibliographic Details
Main Authors: Yuejuan Li, Baichun Hu, Zhibin Wang, Jianhua He, Yaoliang Zhang, Jian Wang, Lijie Guan
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
isobavachalcone
RNA sequencing
enzyme activity
pyruvate dehydrogenase
homology modeling
molecular dynamics simulation
Online Access:https://www.mdpi.com/1422-0067/22/10/5163

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