Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses

Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses

CD4+ T cells play an important role in regulating silica-induced inflammation and fibrosis. Recent studies showed that Wnt/β-catenin pathway could modulate the function and the differentiation of CD4+ T cells. Therefore, Wnt/β-catenin pathway may participate in the development and progress of silico...

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Bibliographic Details
Main Authors: Wujing Dai, Fangwei Liu, Chao Li, Yiping Lu, Xiaowei Lu, Sitong Du, Ying Chen, Dong Weng, Jie Chen
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/6235614

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