Trauma Induces Interleukin-17A Expression on Th17 Cells and CD4+ Regulatory T Cells as Well as Platelet Dysfunction

Trauma Induces Interleukin-17A Expression on Th17 Cells and CD4+ Regulatory T Cells as Well as Platelet Dysfunction

Background: The organism's immune response to trauma is distinctively controlled, its dysregulation leading to severe post-traumatic complications. Platelets, CD4+ regulatory T cells (CD4+ Tregs) and T helper 17 (Th17) cells have been identified to participate in the post-traumatic immune respo...

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Bibliographic Details
Main Authors: Friederike Hefele, Alexander Ditsch, Niels Krysiak, Charles C. Caldwell, Peter Biberthaler, Martijn van Griensven, Stefan Huber-Wagner, Marc Hanschen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
T helper 17 cells
CD4+ regulatory T cells
trauma
hemostasis
IL-17A
flow cytometry
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02389/full

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