'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix?

Bone fractures frequently occur in elderly persons even after low-energy trauma. Given that the young individuals would not sustain a fracture under such conditions, it is clear that the main cause of easy bone fracturing originates from the structural and compositional characteristics of the aged b...

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Main Authors:	Milovanović Petar, Đurić-Srejić Marija
Format:	Article
Language:	English
Published:	University of Belgrade, Medical Faculty 2016-01-01
Series:	Medicinski Podmladak
Subjects:	Bone nano fracture aging mineral crystals
Online Access:	http://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2016/0369-15271601020M.pdf

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spelling	doaj-9d0fd0768a834b59a68ddbca0d6d980b2020-11-24T22:39:57ZengUniversity of Belgrade, Medical FacultyMedicinski Podmladak0369-15272466-55252016-01-01671202410.5937/medpodm1601020M0369-15271601020M'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix?Milovanović Petar0Đurić-Srejić Marija1University of Belgrade, Faculty of Medicine - Institute of Anatomy, Belgrade, SerbiaUniversity of Belgrade, Faculty of Medicine - Institute of Anatomy, Belgrade, SerbiaBone fractures frequently occur in elderly persons even after low-energy trauma. Given that the young individuals would not sustain a fracture under such conditions, it is clear that the main cause of easy bone fracturing originates from the structural and compositional characteristics of the aged bone itself. Observing bone, from macro- to nano-level, shows us the complexity of bone hierarchical organization and reveals various determinants of bone strength. In particular, recent studies focusing on bone at nano-scale revealed distinctive features of the bone matrix that could provide additional explanation for the increased bone fragility in advanced age, independent from age-related effects at other levels of bone hierarchical structure.http://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2016/0369-15271601020M.pdfBonenanofractureagingmineral crystals
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Milovanović Petar Đurić-Srejić Marija
spellingShingle	Milovanović Petar Đurić-Srejić Marija 'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix? Medicinski Podmladak Bone nano fracture aging mineral crystals
author_facet	Milovanović Petar Đurić-Srejić Marija
author_sort	Milovanović Petar
title	'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix?
title_short	'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix?
title_full	'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix?
title_fullStr	'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix?
title_full_unstemmed	'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix?
title_sort	'going nano' in the field of osteology: is bone fragility already determined at the level of bone mineralized matrix?
publisher	University of Belgrade, Medical Faculty
series	Medicinski Podmladak
issn	0369-1527 2466-5525
publishDate	2016-01-01
description	Bone fractures frequently occur in elderly persons even after low-energy trauma. Given that the young individuals would not sustain a fracture under such conditions, it is clear that the main cause of easy bone fracturing originates from the structural and compositional characteristics of the aged bone itself. Observing bone, from macro- to nano-level, shows us the complexity of bone hierarchical organization and reveals various determinants of bone strength. In particular, recent studies focusing on bone at nano-scale revealed distinctive features of the bone matrix that could provide additional explanation for the increased bone fragility in advanced age, independent from age-related effects at other levels of bone hierarchical structure.
topic	Bone nano fracture aging mineral crystals
url	http://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2016/0369-15271601020M.pdf
work_keys_str_mv	AT milovanovicpetar goingnanointhefieldofosteologyisbonefragilityalreadydeterminedatthelevelofbonemineralizedmatrix AT đuricsrejicmarija goingnanointhefieldofosteologyisbonefragilityalreadydeterminedatthelevelofbonemineralizedmatrix
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'GOING NANO' in the field of osteology: Is bone fragility already determined at the level of bone mineralized matrix?

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