Lhx2 is required for patterning and expansion of a distinct progenitor cell population committed to eye development.

Progenitor cells committed to eye development become specified in the prospective forebrain and develop subsequently into the optic vesicle and the optic cup. The optic vesicle induces formation of the lens placode in surface ectoderm from which the lens develops. Numerous transcription factors are...

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Bibliographic Details
Main Authors: Anna-Carin Hägglund, Lina Dahl, Leif Carlsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3158764?pdf=render