Dynamics of the Type I Interferon Response During Immunosuppressive Therapy in Rheumatoid Arthritis

Dynamics of the Type I Interferon Response During Immunosuppressive Therapy in Rheumatoid Arthritis

Objective: The type I interferon (IFN) response in rheumatoid arthritis (RA) has been extensively studied in relation to therapy with biological DMARDs (bDMARDs). However, the effect of conventional synthetic (cs)DMARDs and glucocorticoids (GCs) on IFN response gene (IRG) expression remains largely...

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Bibliographic Details
Main Authors: Tamarah D. de Jong, Tanja Snoek, Elise Mantel, Conny J. van der Laken, Ronald F. van Vollenhoven, Willem F. Lems
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
interferon
interferon response
biomarker
immunosuppression
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00902/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00902/full

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