Exploration of the glutamate-mediated retinal excitotoxic damage: a rat model of retinal neurodegeneration

AIM: To explore the more suitable concentration of glutamate or N-methyl-D-aspartic acid (NMDA) for intravitreal injection to establish a rat model of retinal neurodegeneration. METHODS: We injected different doses of glutamate (20 or 50 nmol) or NMDA (40 nmol) into the vitreous chambers of rats, t...

Full description

Bibliographic Details
Main Authors: Ling Gao, Qi-Jun Zheng, Li-Qian-Yu Ai, Kai-Jian Chen, Yuan-Guo Zhou, Jian Ye, Wei Liu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-11-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2018/11/20181103.pdf