ShenLian Extract Enhances TGF-β Functions in the Macrophage-SMC Unit and Stabilizes Atherosclerotic Plaques

ShenLian Extract Enhances TGF-β Functions in the Macrophage-SMC Unit and Stabilizes Atherosclerotic Plaques

Background/Aim: Macrophage polarization and phenotypic switching of smooth muscle cells (SMCs) are multi-faceted events dominating atherosclerosis (AS) progression. TGF-β was proved to been one of the bridge on the crosstalk between macrophage and SMC. ShenLian (SL) was extracted from a potent anti-...

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Bibliographic Details
Main Authors: Li Liu, Qi Li, Jie Yin, Zheng Zhao, Lidong Sun, Qingsen Ran, Xinke Du, Yajie Wang, Yujie Li, Qing Yang, Ying Chen, Xiaogang Weng, Weiyan Cai, Xiaoxin Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
atherosclerotic plaques stability
transforming growth factor-β
smooth muscle cells phenotype switching
macrophage polarization
shenlian extract
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.669730/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.669730/full

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