Hypertonic saline reduces vascular leakage in a mouse model of severe dengue.

Dengue (DEN) is a mosquito-borne viral disease and represents a serious public health threat and an economical burden throughout the tropics. Dengue clinical manifestations range from mild acute febrile illness to severe DEN hemorrhagic fever/DEN shock syndrome (DHF/DSS). Currently, resuscitation wi...

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Bibliographic Details
Main Authors: Grace Kai Xin Tan, Jowin Kai Wei Ng, Kar Wai Tan, Veronique Angeli, Shabbir Moochhala, Eng Eong Ooi, Sylvie Alonso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3630109?pdf=render