<it>BRAF </it>mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status

<it>BRAF </it>mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status

<p>Abstract</p> <p>Background</p> <p>BRAF is a member of RAF family of serine/threonine kinases and mediates cellular responses to growth signals through the RAS-RAF-MAP kinase pathway. Activating mutations in <it>BRAF </it>have recently been found in about...

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Bibliographic Details
Main Authors: Bennett Graeme, Ruszkiewicz Andrew, Kawakami Kazuyuki, Qi Li Wei, Moore James, Iacopetta Barry
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/2

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