<it>BRAF </it>mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status
<p>Abstract</p> <p>Background</p> <p>BRAF is a member of RAF family of serine/threonine kinases and mediates cellular responses to growth signals through the RAS-RAF-MAP kinase pathway. Activating mutations in <it>BRAF </it>have recently been found in about...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-01-01
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| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/5/1/2 |