Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour

Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour

Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause sh...

Full description

Bibliographic Details
Main Authors: Sanjay de Mel, Zarni Soe, Benjamin Wong, Ching Ching Ong, Lynette Teo, Lip Kun Tan
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2016/6801916
id doaj-9cec1e65321b45d492da62b5bbacb208
record_format Article
spelling doaj-9cec1e65321b45d492da62b5bbacb2082020-11-24T22:38:46ZengHindawi LimitedCase Reports in Transplantation2090-69432090-69512016-01-01201610.1155/2016/68019166801916Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory PseudotumourSanjay de Mel0Zarni Soe1Benjamin Wong2Ching Ching Ong3Lynette Teo4Lip Kun Tan5Department of Haematology-Oncology, National University Cancer Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block Level 7, 119228, SingaporeDepartment of Haematology-Oncology, National University Cancer Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block Level 7, 119228, SingaporeDepartment of Pathology, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartment of Diagnostic Imaging, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartment of Diagnostic Imaging, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartments of Laboratory Medicine and Haematology-Oncology, National University Cancer Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block Level 7, 119228, SingaporeInflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause she underwent a reduced intensity conditioning stem cell transplant (SCT) successfully and currently remains well and in remission. On repeat liver MRI after SCT, the IPT was seen to be resolving. To the best of our knowledge this is the first report of an adult patient with hepatic IPT successfully undergoing SCT. The reduction in size of the IPT after SCT also suggests an inflammatory rather than an infective aetiology for IPT.http://dx.doi.org/10.1155/2016/6801916
collection DOAJ
language English
format Article
sources DOAJ
author Sanjay de Mel
Zarni Soe
Benjamin Wong
Ching Ching Ong
Lynette Teo
Lip Kun Tan
spellingShingle Sanjay de Mel
Zarni Soe
Benjamin Wong
Ching Ching Ong
Lynette Teo
Lip Kun Tan
Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
Case Reports in Transplantation
author_facet Sanjay de Mel
Zarni Soe
Benjamin Wong
Ching Ching Ong
Lynette Teo
Lip Kun Tan
author_sort Sanjay de Mel
title Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_short Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_full Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_fullStr Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_full_unstemmed Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
title_sort successful stem cell transplantation in a patient with pretransplant hepatic inflammatory pseudotumour
publisher Hindawi Limited
series Case Reports in Transplantation
issn 2090-6943
2090-6951
publishDate 2016-01-01
description Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause she underwent a reduced intensity conditioning stem cell transplant (SCT) successfully and currently remains well and in remission. On repeat liver MRI after SCT, the IPT was seen to be resolving. To the best of our knowledge this is the first report of an adult patient with hepatic IPT successfully undergoing SCT. The reduction in size of the IPT after SCT also suggests an inflammatory rather than an infective aetiology for IPT.
url http://dx.doi.org/10.1155/2016/6801916
work_keys_str_mv AT sanjaydemel successfulstemcelltransplantationinapatientwithpretransplanthepaticinflammatorypseudotumour
AT zarnisoe successfulstemcelltransplantationinapatientwithpretransplanthepaticinflammatorypseudotumour
AT benjaminwong successfulstemcelltransplantationinapatientwithpretransplanthepaticinflammatorypseudotumour
AT chingchingong successfulstemcelltransplantationinapatientwithpretransplanthepaticinflammatorypseudotumour
AT lynetteteo successfulstemcelltransplantationinapatientwithpretransplanthepaticinflammatorypseudotumour
AT lipkuntan successfulstemcelltransplantationinapatientwithpretransplanthepaticinflammatorypseudotumour
_version_ 1725711958974398464

Similar Items