An epigenetic vaccine model active in the prevention and treatment of melanoma

<p>Abstract</p> <p>Background</p> <p>Numerous immune genes are epigenetically silenced in tumor cells and agents such as histone deacetylase inhibitors (HDACi), which reverse these effects, could potentially be used to develop therapeutic vaccines. The conversion of can...

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Bibliographic Details
Main Authors: Magner William J, Khan A Nazmul H, Tomasi Thomas B
Format: Article
Language:English
Published: BMC 2007-12-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/5/1/64