Colorectal cancer-derived extracellular vesicles induce transformation of fibroblasts into colon carcinoma cells

Abstract Background We reported that horizontal transfer of malignant traits to target cells is a potential pathway to explain cancer dissemination. Although these results were encouraging, they were never corroborated by data showing the molecular mechanisms responsible for the observed phenomenon....

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Bibliographic Details
Main Authors: Mohamed Abdouh, Matteo Floris, Zu-Hua Gao, Vincenzo Arena, Manuel Arena, Goffredo Orazio Arena
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-019-1248-2