Corneal endothelial cells provide evidence of accelerated cellular senescence associated with HIV infection: a case-control study.

Cellular senescence may be a key factor in HIV-related premature biological aging. We assessed features of the corneal endothelium that are known to be associated with biological aging, and cellular senescence markers in HIV-infected adults.Case-control study of 242 HIV-infected adults and 249 match...

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Bibliographic Details
Main Authors: Sophia Pathai, Stephen D Lawn, Paul G Shiels, Helen A Weiss, Colin Cook, Robin Wood, Clare E Gilbert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3584030?pdf=render