A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks

A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks

<p>Abstract</p> <p>Background</p> <p>Formation and repair of DNA single-strand breaks are important parameters in the assessment of DNA damage and repair occurring in live cells. The 'Fluorimetric Detection of Alkaline DNA Unwinding (FADU)' method [Birnboim HC...

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Bibliographic Details
Main Authors: Müller Marcus, Leake Alan, Sindlinger Thilo, Pfeiffer Ragen, Moreno-Villanueva María, Kirkwood Thomas BL, Bürkle Alexander
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/9/39

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