Eye Irritation Test of Fel Ursi & Bovis Calculus Pharmacopuncture Solutions for Eye Drop

• Main Author: Hyeong-sik Seo
• Format: Article
• Language: English
• Published: Korean Pharmacopuncture Institute 2008-09-01
• Series: Journal of Pharmacopuncture
• Subjects: Fel Ursi & Bovis Calculus pharmacopuncture solution; eye irritation test; eye drop
• Online Access: http://dx.doi.org/10.3831/KPI.2008.11.3.099

Objective : This study was done to investigate the safety of Fel Ursi & Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods : The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration(2005. 10. 21, KFDA 2005-60). After Fel Ursi & Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, the author observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results : 1. After Fel Ursi & Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn't physical problem at 9 rabbits. 2. After Fel Ursi & Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn’t eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Conclusions I suggested that Fel Ursi & Bovis Calculus pharmacopuncture solution didn’t induced eye irritation in rabbits.