A Rapid Genome-wide MicroRNA Screen Identifies miR-14 as a Modulator of Hedgehog Signaling
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression by binding to sequences within the 3′ UTR of mRNAs. Because miRNAs bind to short sequences with partial complementarity, target identification is challenging. To complement the existing target prediction algorithms, we devised...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-06-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714004008 |