STL-based analysis of TRAIL-induced apoptosis challenges the notion of type I/type II cell line classification.

STL-based analysis of TRAIL-induced apoptosis challenges the notion of type I/type II cell line classification.

Extrinsic apoptosis is a programmed cell death triggered by external ligands, such as the TNF-related apoptosis inducing ligand (TRAIL). Depending on the cell line, the specific molecular mechanisms leading to cell death may significantly differ. Precise characterization of these differences is cruc...

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Bibliographic Details
Main Authors: Szymon Stoma, Alexandre Donzé, François Bertaux, Oded Maler, Gregory Batt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3649977?pdf=render

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