Decomposition of abnormal free locomotor behavior in a rat model of Parkinson´s disease

Decomposition of abnormal free locomotor behavior in a rat model of Parkinson´s disease

Poverty of spontaneous movement, slowed execution and reduced amplitudes of movement (akinesia, brady- and hypokinesia) are cardinal motor manifestations of Parkinson´s disease that can be modeled in experimental animals by brain lesions affecting midbrain dopaminergic neurons. Most behavio...

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Bibliographic Details
Main Authors: Benjamin eGrieb, Constantin eVon Nicolai, Gerhard eEngler, Andrew eSharott, Ismini ePapageorgiou, Wolfgang eHamel, Andreas K. Engel, Christian K. Moll
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Systems Neuroscience
Subjects:
Parkinson Disease
spontaneous activity
6-OHDA lesions
Stereology
video monitoring
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00095/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsys.2013.00095/full

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