Synthesis and Single Crystal Structures of N-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives

A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-...

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Main Authors:	Guoxiong Hua, Cameron L. Carpenter-Warren, David B. Cordes, Alexandra M. Z. Slawin, J. Derek Woollins
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Molecules
Subjects:	<i>N</i>-Substituted Benzamides Woollins’ reagent selenation reagent reduction reagent single crystal X-ray structures
Online Access:	https://www.mdpi.com/1420-3049/26/8/2367

id	doaj-9c982343996940dcbdf41f1fcde7ead0
record_format	Article
spelling	doaj-9c982343996940dcbdf41f1fcde7ead02021-04-19T23:02:51ZengMDPI AGMolecules1420-30492021-04-01262367236710.3390/molecules26082367Synthesis and Single Crystal Structures of <i>N</i>-Substituted Benzamides and Their Chemoselective Selenation/Reduction DerivativesGuoxiong Hua0Cameron L. Carpenter-Warren1David B. Cordes2Alexandra M. Z. Slawin3J. Derek Woollins4EaStCHEM School of Chemistry, University of St Andrews, St Andrews Fife KY16 9ST, UKEaStCHEM School of Chemistry, University of St Andrews, St Andrews Fife KY16 9ST, UKEaStCHEM School of Chemistry, University of St Andrews, St Andrews Fife KY16 9ST, UKEaStCHEM School of Chemistry, University of St Andrews, St Andrews Fife KY16 9ST, UKEaStCHEM School of Chemistry, University of St Andrews, St Andrews Fife KY16 9ST, UKA series of <i>N</i>-aryl-<i>N</i>-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding <i>N</i>-aryl-<i>N</i>-(arylenethyl) benzoselenoamides in good yields. Five representative single crystal X-ray structures are discussed.https://www.mdpi.com/1420-3049/26/8/2367<i>N</i>-Substituted BenzamidesWoollins’ reagentselenation reagentreduction reagentsingle crystal X-ray structures
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Guoxiong Hua Cameron L. Carpenter-Warren David B. Cordes Alexandra M. Z. Slawin J. Derek Woollins
spellingShingle	Guoxiong Hua Cameron L. Carpenter-Warren David B. Cordes Alexandra M. Z. Slawin J. Derek Woollins Synthesis and Single Crystal Structures of <i>N</i>-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives Molecules <i>N</i>-Substituted Benzamides Woollins’ reagent selenation reagent reduction reagent single crystal X-ray structures
author_facet	Guoxiong Hua Cameron L. Carpenter-Warren David B. Cordes Alexandra M. Z. Slawin J. Derek Woollins
author_sort	Guoxiong Hua
title	Synthesis and Single Crystal Structures of <i>N</i>-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_short	Synthesis and Single Crystal Structures of <i>N</i>-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_full	Synthesis and Single Crystal Structures of <i>N</i>-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_fullStr	Synthesis and Single Crystal Structures of <i>N</i>-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_full_unstemmed	Synthesis and Single Crystal Structures of <i>N</i>-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives
title_sort	synthesis and single crystal structures of <i>n</i>-substituted benzamides and their chemoselective selenation/reduction derivatives
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2021-04-01
description	A series of <i>N</i>-aryl-<i>N</i>-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding <i>N</i>-aryl-<i>N</i>-(arylenethyl) benzoselenoamides in good yields. Five representative single crystal X-ray structures are discussed.
topic	<i>N</i>-Substituted Benzamides Woollins’ reagent selenation reagent reduction reagent single crystal X-ray structures
url	https://www.mdpi.com/1420-3049/26/8/2367
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Synthesis and Single Crystal Structures of <i>N</i>-Substituted Benzamides and Their Chemoselective Selenation/Reduction Derivatives

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