Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019

Abstract Background Cardiovascular diseases (CVDs) are the number one cause of global mortality representing about one third of all deaths across the world. The objective of the present study was to model the global trend in disability-adjusted life years (DALY) and its components due to CVD over th...

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Main Authors: Fatemeh Masaebi, Masoud Salehi, Maryam Kazemi, Nasim Vahabi, Mehdi Azizmohammad Looha, Farid Zayeri
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Public Health
Subjects:
Online Access:https://doi.org/10.1186/s12889-021-11348-w
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spelling doaj-9c8cbd389143479aa89a71743b663f482021-07-04T11:16:36ZengBMCBMC Public Health1471-24582021-06-0121111310.1186/s12889-021-11348-wTrend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019Fatemeh Masaebi0Masoud Salehi1Maryam Kazemi2Nasim Vahabi3Mehdi Azizmohammad Looha4Farid Zayeri5Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical SciencesHealth Management and Economics Research Center and Department of Biostatistics, School of Public Health, Iran University of Medical SciencesDepartment of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical SciencesInformatics Institute, University of FloridaDepartment of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical SciencesPrevention of Cardiovascular Disease Research Center, Shahid Beheshti University of Medical SciencesAbstract Background Cardiovascular diseases (CVDs) are the number one cause of global mortality representing about one third of all deaths across the world. The objective of the present study was to model the global trend in disability-adjusted life years (DALY) and its components due to CVD over the past three decades. We also aimed to evaluate the longitudinal relationship between CVD DALY and Human Development Index (HDI) in this period of time. Methods The age-standardized rates of years lost due to disability (YLD), years of life lost (YLL) and DALY were extracted for cardiovascular diseases from the Global Burden of Disease (GBD) Study 2019 in years 1990 to 2019. Additionally, the United Nations Development Programme (UNDP) database was used to retrieve HDI values for all world countries at the same period time. The trend analysis was performed using the joinpoint regression model. Results The obtained revealed a significant downward trend for DALY and its components with the average annual percent change of − 1.0, − 0.3 and − 1.1 per 100,000 population, respectively for DALY, YLD and YLL. We also found that countries with high/very high levels of HDI have remarkably experienced steeper declining slope of trend than those in lower levels of HDI over the study period. Conclusions Although the observed decreasing trend of CVD burden is a hopeful message for all world countries, the considerable gap in slope of trend between richer and poorer parts of the world is a serious alarm for health policy makers. Regarding this, there is an urgent need to put more efforts on implementing preventive programs, improving the level of patients’ care and providing efficient treatment, especially in regions with lower levels of HDI.https://doi.org/10.1186/s12889-021-11348-wCardiovascular diseasesDisability-adjusted life yearsHuman development indexTrend analysis
collection DOAJ
language English
format Article
sources DOAJ
author Fatemeh Masaebi
Masoud Salehi
Maryam Kazemi
Nasim Vahabi
Mehdi Azizmohammad Looha
Farid Zayeri
spellingShingle Fatemeh Masaebi
Masoud Salehi
Maryam Kazemi
Nasim Vahabi
Mehdi Azizmohammad Looha
Farid Zayeri
Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019
BMC Public Health
Cardiovascular diseases
Disability-adjusted life years
Human development index
Trend analysis
author_facet Fatemeh Masaebi
Masoud Salehi
Maryam Kazemi
Nasim Vahabi
Mehdi Azizmohammad Looha
Farid Zayeri
author_sort Fatemeh Masaebi
title Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019
title_short Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019
title_full Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019
title_fullStr Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019
title_full_unstemmed Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019
title_sort trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019
publisher BMC
series BMC Public Health
issn 1471-2458
publishDate 2021-06-01
description Abstract Background Cardiovascular diseases (CVDs) are the number one cause of global mortality representing about one third of all deaths across the world. The objective of the present study was to model the global trend in disability-adjusted life years (DALY) and its components due to CVD over the past three decades. We also aimed to evaluate the longitudinal relationship between CVD DALY and Human Development Index (HDI) in this period of time. Methods The age-standardized rates of years lost due to disability (YLD), years of life lost (YLL) and DALY were extracted for cardiovascular diseases from the Global Burden of Disease (GBD) Study 2019 in years 1990 to 2019. Additionally, the United Nations Development Programme (UNDP) database was used to retrieve HDI values for all world countries at the same period time. The trend analysis was performed using the joinpoint regression model. Results The obtained revealed a significant downward trend for DALY and its components with the average annual percent change of − 1.0, − 0.3 and − 1.1 per 100,000 population, respectively for DALY, YLD and YLL. We also found that countries with high/very high levels of HDI have remarkably experienced steeper declining slope of trend than those in lower levels of HDI over the study period. Conclusions Although the observed decreasing trend of CVD burden is a hopeful message for all world countries, the considerable gap in slope of trend between richer and poorer parts of the world is a serious alarm for health policy makers. Regarding this, there is an urgent need to put more efforts on implementing preventive programs, improving the level of patients’ care and providing efficient treatment, especially in regions with lower levels of HDI.
topic Cardiovascular diseases
Disability-adjusted life years
Human development index
Trend analysis
url https://doi.org/10.1186/s12889-021-11348-w
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