Induction of UDP-glucuronosyltransferase 1A by naturally occurring phytochemicals in human hepatoma cells

Induction of UDP-glucuronosyltransferase 1A by naturally occurring phytochemicals in human hepatoma cells

UDP-glucuronosyltransferases (UGTs) are important detoxification and drug-metabolizing enzymes, which catalyse the glucuronidation of exogenous and endogenous chemicals. The anti-carcinogenic activity of dietary phytochemicals is partly attributed to the induction of phase II enzymes, including UGT1...

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Bibliographic Details
Main Authors: Violetta Krajka-Kuźniak, Adam Krysztofiak, Jarosław Paluszczak
Format: Article
Language:English
Published: Poznan University of Medical Sciences 2014-09-01
Series:Journal of Medical Science
Subjects:
tannic acid
protocatechuic acid
indole-3-carbinol
phenethyl isothiocyanate
UGT1A
HepG2
Online Access:https://jms.ump.edu.pl/index.php/JMS/article/view/69

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