Synthesis, Crystal Structure, and Biological Activity of a Multidentate Calix[4]arene Ligand Doubly Functionalized by 2-Hydroxybenzeledene-Thiosemicarbazone

Synthesis, Crystal Structure, and Biological Activity of a Multidentate Calix[4]arene Ligand Doubly Functionalized by 2-Hydroxybenzeledene-Thiosemicarbazone

The design and synthesis of a novel tert-butyl-calix[4]arene functionalized at 1, 3 positions of the lower rim with two terminal 2-hydroxybenzeledene-thiosemicarbazone moieties is reported. The new ligand with multi-dentate chelating properties was fully characterized by several techniques: ESI-Mass...

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Bibliographic Details
Main Authors: Ehsan Bahojb Noruzi, Behrouz Shaabani, Silvano Geremia, Neal Hickey, Patrizia Nitti, Hossein Samadi Kafil
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
thiosemicarbazone
calix[4]arene
metal complex
x-ray structure
antimicrobial
anticancer
Online Access:https://www.mdpi.com/1420-3049/25/2/370

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