Assessment of the Bone Healing Process Mediated by Periosteum-Derived Mesenchymal Stem Cells’ Secretome and a Xenogenic Bioceramic—An In Vivo Study in the Rabbit Critical Size Calvarial Defect Model

Assessment of the Bone Healing Process Mediated by Periosteum-Derived Mesenchymal Stem Cells’ Secretome and a Xenogenic Bioceramic—An In Vivo Study in the Rabbit Critical Size Calvarial Defect Model

The mesenchymal stem cell (MSC) secretome has been considered an innovative therapeutic biological approach, able to modulate cellular crosstalk and functionality for enhanced tissue repair and regeneration. This study aims to evaluate the functionality of the secretome isolated from periosteum-deri...

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Bibliographic Details
Main Authors: Mindaugas Pranskunas, Egidijus Šimoliūnas, Milda Alksne, Victor Martin, Pedro Sousa Gomes, Algirdas Puisys, Algirdas Kaupinis, Gintaras Juodzbalys
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Materials
Subjects:
secretome
mesenchymal stem cells (MSCs)
bone regeneration
bone defect
Online Access:https://www.mdpi.com/1996-1944/14/13/3512

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https://www.mdpi.com/1996-1944/14/13/3512

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