Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting.

Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting.

<h4>Background</h4>Important support functions, including promotion of tumor growth, angiogenesis, and invasion, have been attributed to the different cell types populating the tumor stroma, i.e., endothelial cells, cancer-associated fibroblasts, pericytes, and infiltrating inflammatory...

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Bibliographic Details
Main Authors: Kristian Pietras, Jessica Pahler, Gabriele Bergers, Douglas Hanahan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Medicine
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18232728/?tool=EBI

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