Why Inhibition of IL-23 Lacked Efficacy in Ankylosing Spondylitis

Why Inhibition of IL-23 Lacked Efficacy in Ankylosing Spondylitis

The term spondyloarthritis pertains to both axial and peripheral arthritis including ankylosing spondylitis (AS) and psoriatic arthritis (PsA), which is strongly linked to psoriasis and also the arthritis associated with inflammatory bowel disease. The argument supporting the role for IL-23 across t...

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Bibliographic Details
Main Authors: Dennis McGonagle, Abdulla Watad, Kassem Sharif, Charlie Bridgewood
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
IL-23
psoriatic arthritis
ankylosing spondylitis
enthesis
IL-17
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.614255/full

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