A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization.
Apico-basal polarity establishment is a seminal process in tissue morphogenesis. To function properly it is often imperative that epithelial cells limit apical membrane formation to a single domain. We previously demonstrated that signaling by the small GTPase Cdc42, together with its guanine nucleo...
Main Authors: | Lucas J M Bruurs, Mirjam C van der Net, Susan Zwakenberg, Fried J T Zwartkruis, Johannes L Bos |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC6224091?pdf=render |
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